Origin & tradition
Not traditional as an isolate, though quercetin-rich foods (onions, capers) are dietary staples.
Western tradition · Flavonoid
Quercetin 槲皮素
A widespread dietary flavonoid, studied as a senolytic partner (with dasatinib) and anti-inflammatory.
131ClinicalTrials.gov matched
272PubMed RCT records
203Meta-analysis records
273+PubMed records
QuercetinKey active compound
Data definition. Matched records include all indexed medical endpoints for this intervention — not only longevity. Longevity-relevant records are screened separately and cited in the evidence summary below. Counts are matched-record volumes, not de-duplicated trials and not efficacy claims.
Why longevity buyers care
Key active: Quercetin (flavonoid).
Quercetin modulates inflammation and, combined with dasatinib (D+Q), is the most-studied senolytic regimen in early human trials for senescence-associated conditions.
Effect summary
Studied health outcomes
Editorial summary — This table is curated by hand from published research consensus, not automatically calculated from our trial database. Grades reflect our interpretation of the literature. Treat as a starting point, not a definitive verdict. See the Evidence panel below for the underlying trial and paper counts sourced directly from ClinicalTrials.gov and PubMed.
| Health outcome | Effect | Magnitude | Grade |
|---|---|---|---|
| Inflammation (CRP) | Decreases | Minor | B |
| Systolic blood pressure | Decreases | Minor | B |
| Allergy symptoms (histamine) | Decreases | Moderate | B |
| Senescent cell burden — Mostly preclinical; one early human pilot | Decreases | Minor | D |
| LDL oxidation | Decreases | Minor | C |
| Aerobic endurance | Increases | Minor | C |
Grade: A = robust RCTs · B = several RCTs / meta-analysis · C = limited or mixed RCTs · D = observational or early data
Dosage guidance
How Quercetin is typically used
- Typical dose
- 500–1,000 mg/day
- Form
- capsule; Quercefit (phytosome) preferred for absorption
- Timing
- with meals
Standard quercetin has poor bioavailability. Quercefit (quercetin-phospholipid complex) is ~20× better absorbed. For senolytic use, intermittent high-dose protocols (e.g. 1,000 mg × 2 days, with Dasatinib off-label) are under investigation.
Informational only — not a prescription or personalised medical advice. Consult a qualified clinician before starting any supplement or medication.
Evidence summary
What the research actually says
70Evidence confidence
Extensive human-trial evidence272 randomized controlled trials · 203 meta-analyses / systematic reviews
Early human senolytic trials (D+Q); anti-inflammatory data
Quercetin modulates inflammation and, combined with dasatinib (D+Q), is the most-studied senolytic regimen in early human trials for senescence-associated conditions.
131registered clinical trials reference this intervention
3selected from 273+ PubMed papers (longevity / aging angle)
Key active: Quercetin (flavonoid).
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-07-19. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
Evidence collections
Quercetin appears in
Compare the evidence
Related ingredients
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Urolithin A尿石素 A
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Rapamycin (Sirolimus)雷帕霉素
75The single most reproducible lifespan-extending molecule in animals — a prescription drug under off-label longevity study.
Compare the evidence
How Quercetin stacks up
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