Origin & tradition
Not traditional: fisetin occurs in strawberries and other plants; its senolytic profile emerged from aging research.
Western tradition · Senolytic · flavonoid
Fisetin 漆黄素
A plant flavonoid and leading senolytic candidate — clearing “zombie” senescent cells in animal models.
Why longevity buyers care
Key active: Fisetin (flavonoid senolytic).
Fisetin selectively clears senescent cells and extended lifespan and healthspan in aged mice; human senolytic trials are early-stage, making this promising-but-unproven.
Evidence summary
What the research actually says
66Evidence confidence
Early / limited human trials7 randomized controlled trials · 12 meta-analyses / systematic reviews
Strong animal senolytic data; human trials early
Fisetin selectively clears senescent cells and extended lifespan and healthspan in aged mice; human senolytic trials are early-stage, making this promising-but-unproven.
34registered clinical trials reference this intervention
3selected from 22+ PubMed papers (longevity / aging angle)
Key active: Fisetin (flavonoid senolytic).
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-06-06. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
Compare the evidence
How Fisetin stacks up
Verified suppliers
No verified Fisetin suppliers listed yet
Tell us what you need and we will source verified suppliers for you.