Methodology · evidence standard方法论 · 证据标准

How we decide what counts as real longevity evidence.我们如何判断什么才算真正的长寿证据。

Longevity Atlas is built for decisions, not hype. Our grading starts with public primary sources, separates human evidence from noise, and keeps commercial claims inside defensible boundaries.Longevity Atlas 服务决策,而不是炒作。我们的评级从公开一手来源出发,把人体证据从噪音中拆出来,并让商业宣称保持在可防守边界内。

Principles原则

The rubric is designed to resist marketing pressure.这套尺子专门用来抵抗营销压力。

Human evidence outranks paper volume人体证据高于论文数量

A single relevant randomized human trial can matter more than hundreds of mechanistic or cell studies. We separate RCTs and meta-analyses from broad literature counts.一项相关的人体随机试验,可能比数百篇机制或细胞研究更重要。我们把 RCT 和 meta 分析从泛论文数量中拆出来看。

Null results are part of the product无效结果也是产品的一部分

A useful dossier does not only collect supportive studies. It surfaces the mixed, weak, or negative evidence that buyers, regulators, and clinicians need to see.有用的报告不能只收集支持性研究。它必须展示买家、监管方和临床人员需要看到的矛盾、弱证据或负面证据。

East and West use one rubric东西方使用同一把尺

Reishi, ginseng, NMN, rapamycin, berberine, and urolithin A should not be judged by different marketing languages. Tradition is context; human evidence is the grading spine.灵芝、人参、NMN、雷帕霉素、小檗碱、尿石素 A 不能用不同营销语言判断。传统是背景,人体证据才是评级主轴。

Evidence tiers证据等级

Counts are weighted by study type, not raw volume.数量按研究类型加权,而不是粗暴看总量。

Level 3

Extensive human-trial evidence

100+ RCTs or 50+ meta-analyses

Level 2

Human RCT evidence

10+ RCTs

Level 1

Early / limited human trials

1-9 RCTs

Level 0

Preclinical / mechanistic

No clear human RCT base yet

Source hierarchy来源层级

What we trust first.我们优先相信什么。

Primary registries一手注册库

ClinicalTrials.gov records show registered human studies, status, and study design. They are not proof of efficacy by themselves, but they anchor the landscape.ClinicalTrials.gov 记录展示已注册人体研究、状态和研究设计。它本身不等于有效性证明,但能锚定研究全景。

Peer-reviewed literature同行评审文献

PubMed records help identify RCTs, reviews, and mechanistic literature. The dossier then separates commercially useful evidence from background noise.PubMed 记录帮助识别 RCT、综述和机制文献。报告会进一步把商业有用证据和背景噪音拆开。

Commercial reality商业现实

Supplier readiness, standardization, third-party testing, and claim risk matter because evidence only becomes useful when a buyer can act on it.供应商就绪度、标准化、第三方检测和宣称风险同样重要,因为证据只有能被买家行动化才有价值。

Boundary边界

We are an evidence intelligence layer, not a medical provider.我们是循证情报层,不是医疗服务者。

Longevity Atlas does not diagnose, treat, prescribe, or replace licensed clinical care. We help buyers and private clients ask better questions before they commit money or trust.Longevity Atlas 不诊断、不治疗、不开处方,也不替代持牌医疗服务。我们帮助买家和私人客户在投入金钱或信任之前,问出更好的问题。

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