Origin & tradition
Not traditional: GlyNAC is a research-driven combination targeting age-related glutathione decline.
Western tradition · Glutathione precursors
GlyNAC (Glycine + NAC) 甘氨酸 + N-乙酰半胱氨酸
A glutathione-restoring amino-acid pair with promising small trials on oxidative stress and aging markers.
Why longevity buyers care
Key active: Glycine + N-acetylcysteine.
Glycine and N-acetylcysteine restore glutathione synthesis; small randomized and pilot trials in older adults report improved oxidative stress, mitochondrial function, strength, and cognition — promising but early.
Evidence summary
What the research actually says
71Evidence confidence
Early / limited human trials8 randomized controlled trials · 2 meta-analyses / systematic reviews
Small human RCT/pilot data; glutathione mechanism
Glycine and N-acetylcysteine restore glutathione synthesis; small randomized and pilot trials in older adults report improved oxidative stress, mitochondrial function, strength, and cognition — promising but early.
12registered clinical trials reference this intervention
3selected from 10+ PubMed papers (longevity / aging angle)
- Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial
- Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial
- GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Old Mice Improves Brain Glutathione Deficiency, Oxidative Stress, Glucose Uptake, Mitochondrial Dysfunction, Genomic Damage, Inflammation and Neurotrophic Factors to Reverse Age-Associated Cognitive Decline: Implications for Improving Brain Health in Aging
Key active: Glycine + N-acetylcysteine.
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-06-06. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
Verified suppliers
No verified GlyNAC (Glycine + NAC) suppliers listed yet
Tell us what you need and we will source verified suppliers for you.