Origin & tradition
Not traditional as a supplement, though magnesium-rich foods are universal; modern interest is metabolic and neurological.
Western tradition · Essential mineral
Magnesium 镁
A cofactor for hundreds of enzymes, widely under-consumed, tied to sleep, metabolic, and DNA-repair pathways.
Why longevity buyers care
Key active: Magnesium (glycinate, citrate, threonate).
Magnesium is a cofactor in ATP metabolism, DNA repair, and neuromuscular function; observational and trial data link adequacy to sleep quality, metabolic health, and lower inflammatory aging.
Evidence summary
What the research actually says
77Evidence confidence
Extensive human-trial evidence2,984 randomized controlled trials · 1,017 meta-analyses / systematic reviews
Human trials (sleep, metabolic, BP); broad mechanistic role
Magnesium is a cofactor in ATP metabolism, DNA repair, and neuromuscular function; observational and trial data link adequacy to sleep quality, metabolic health, and lower inflammatory aging.
2,043registered clinical trials reference this intervention
3selected from 1,840+ PubMed papers (longevity / aging angle)
Key active: Magnesium (glycinate, citrate, threonate).
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-06-06. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
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