Eastern tradition · Premium Chinese Tea

Green Tea (EGCG) 绿茶 · 表没食子儿茶素没食子酸酯

The most-studied tea catechin, linked to lifespan and healthspan in models via AMPK, sirtuin and FOXO pathways.

Origin & tradition

Green tea (Longjing, sencha, jasmine bases) has been a daily ritual beverage in China for over a millennium, valued for clarity, digestion, and vitality.

Why longevity buyers care

Key active: Epigallocatechin gallate (EGCG).

EGCG and ECG act as mitohormetic compounds: transient complex-I inhibition activates AMPK (AAK-2), SIRT1 (SIR-2.1), NRF2 (SKN-1) and FOXO (DAF-16), raising stress resistance and reducing fat content in model organisms.

Evidence summary

What the research actually says

88Evidence confidence

Strong preclinical + human trials across cardiometabolic and cognitive endpoints

EGCG and ECG act as mitohormetic compounds: transient complex-I inhibition activates AMPK (AAK-2), SIRT1 (SIR-2.1), NRF2 (SKN-1) and FOXO (DAF-16), raising stress resistance and reducing fat content in model organisms.

278registered clinical trials reference this intervention
3selected from 12+ PubMed papers (longevity / aging angle)
Key active: Epigallocatechin gallate (C22H18O11) · ChEMBL CHEMBL297453 · max clinical phase 3 · natural product

According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed, compound data from EMBL-EBI ChEMBL. Counts auto-refresh weekly; last checked 2026-06-05. They include trials across many endpoints, not only longevity.

Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.

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