Western tradition · Amino acid

Taurine 牛磺酸

An amino acid whose decline was linked to aging in a high-profile 2023 study — with human causality still open.

151ClinicalTrials.gov matched
466PubMed RCT records
134Meta-analysis records
8+PubMed records
TaurineKey active compound

Data definition. Matched records include all indexed medical endpoints for this intervention — not only longevity. Longevity-relevant records are screened separately and cited in the evidence summary below. Counts are matched-record volumes, not de-duplicated trials and not efficacy claims.

Origin & tradition

Not traditional: taurine is abundant in animal tissue and is conditionally essential in humans.

Why longevity buyers care

Key active: Taurine (conditionally essential amino acid).

A 2023 Science study showed taurine declines with age and that supplementation extended healthspan in mice and improved markers in monkeys; whether this translates causally to human longevity is not yet established.

Effect summary

Studied health outcomes

Editorial summary — This table is curated by hand from published research consensus, not automatically calculated from our trial database. Grades reflect our interpretation of the literature. Treat as a starting point, not a definitive verdict. See the Evidence panel below for the underlying trial and paper counts sourced directly from ClinicalTrials.gov and PubMed.
Health outcomeEffectMagnitudeGrade
Cardiovascular markers (lipids, blood pressure)DecreasesModerateB
Exercise performance / enduranceIncreasesModerateB
Systolic blood pressureDecreasesModerateB
Insulin sensitivityIncreasesMinorC
Eye health (retinal taurine levels)IncreasesMinorC

Grade: A = robust RCTs · B = several RCTs / meta-analysis · C = limited or mixed RCTs · D = observational or early data

Dosage guidance

How Taurine is typically used

Typical dose
500–3,000 mg/day
Form
powder or capsule
Timing
any time; pre-workout timing studied for exercise effects

Taurine declines with age in tissues. A 2023 Science paper (Singh et al.) linked taurine deficiency to aging across species. Well-tolerated even at high doses; found naturally in seafood and meat. Vegans tend to have lower levels.

Informational only — not a prescription or personalised medical advice. Consult a qualified clinician before starting any supplement or medication.

Evidence summary

What the research actually says

70Evidence confidence
Extensive human-trial evidence466 randomized controlled trials · 134 meta-analyses / systematic reviews

Strong animal data (2023); human causality unproven

A 2023 Science study showed taurine declines with age and that supplementation extended healthspan in mice and improved markers in monkeys; whether this translates causally to human longevity is not yet established.

151registered clinical trials reference this intervention
    3selected from 8+ PubMed papers (longevity / aging angle)
    Key active: Taurine (conditionally essential amino acid).

    According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-07-19. They include trials across many endpoints, not only longevity.

    Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.

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