Origin & tradition
A common dietary berry (Vaccinium); one of the most polyphenol-dense whole foods, valued for antioxidant anthocyanins long before clinical study.
Western tradition · Polyphenol · anthocyanin
Blueberry 蓝莓
An anthocyanin-rich berry with a real but modest human-trial base for cognitive and vascular healthspan — a food, not a magic-bullet longevity intervention.
47ClinicalTrials.gov matched
77PubMed RCT records
22Meta-analysis records
58+PubMed records
AnthocyaninsKey active compound
Data definition. Matched records include all indexed medical endpoints for this intervention — not only longevity. Longevity-relevant records are screened separately and cited in the evidence summary below. Counts are matched-record volumes, not de-duplicated trials and not efficacy claims.
Why longevity buyers care
Key active: Anthocyanins (polyphenols).
Anthocyanins and their metabolites improve endothelial function and modestly support cognitive performance in older adults across multiple RCTs; effect sizes are moderate and depend on dose, baseline status and duration. No human trial tests lifespan extension — the case is healthspan and cardiometabolic, not longevity per se.
Effect summary
Studied health outcomes
Editorial summary — This table is curated by hand from published research consensus, not automatically calculated from our trial database. Grades reflect our interpretation of the literature. Treat as a starting point, not a definitive verdict. See the Evidence panel below for the underlying trial and paper counts sourced directly from ClinicalTrials.gov and PubMed.
| Health outcome | Effect | Magnitude | Grade |
|---|---|---|---|
| Cognitive performance (older adults) | Increases | Moderate | B |
| Endothelial / vascular function | Increases | Moderate | B |
| Blood pressure | Decreases | Minor | C |
| Lifespan / longevity in humans | No change | Negligible | D |
Grade: A = robust RCTs · B = several RCTs / meta-analysis · C = limited or mixed RCTs · D = observational or early data
Dosage guidance
How Blueberry is typically used
- Typical dose
- ~1 cup fresh (≈150 g) daily, or ~24–26 g/day freeze-dried wild-blueberry powder (common RCT dose)
- Form
- whole fruit or freeze-dried powder
- Timing
- daily with food; effects build over weeks
A food — generally safe at dietary intakes. Concentrated extracts vary widely in anthocyanin content; standardize on anthocyanin dose if formulating. Not a treatment for any disease.
Informational only — not a prescription or personalised medical advice. Consult a qualified clinician before starting any supplement or medication.
Evidence summary
What the research actually says
68Evidence confidence
Human RCT evidence77 randomized controlled trials · 22 meta-analyses / systematic reviews
Multiple human RCTs for cognition and vascular function; modest effects; no lifespan data
Anthocyanins and their metabolites improve endothelial function and modestly support cognitive performance in older adults across multiple RCTs; effect sizes are moderate and depend on dose, baseline status and duration. No human trial tests lifespan extension — the case is healthspan and cardiometabolic, not longevity per se.
47registered clinical trials reference this intervention
3selected from 58+ PubMed papers (longevity / aging angle)
Key active: Anthocyanins (polyphenols).
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-07-19. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
Evidence collections
Blueberry appears in
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