Evidence-graded guides

Longevity supplement guides

Evidence-ranked comparisons and buyer guides — every figure sourced from ClinicalTrials.gov and PubMed, not brand marketing.

Evidence-graded · Adaptogens

Best Adaptogens for Stress and Longevity, Ranked by Clinical Evidence

Ashwagandha, rhodiola, panax ginseng, schisandra — ranked by human RCT count and evidence grade, not marketing. Updated from ClinicalTrials.gov and PubMed.

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Evidence-graded · Functional mushrooms

Best Mushroom Supplements for Longevity: Lion's Mane, Reishi, Turkey Tail and Cordyceps Compared

Lion's mane, reishi, turkey tail, cordyceps — each ranked by human RCT count and evidence tier. Not all mushroom supplements are equal. Fruiting body vs mycelium explained.

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Evidence-graded · NAD+ precursors

NMN vs NR vs Nicotinamide: Which NAD+ Booster Has the Best Evidence?

NMN, NR, and nicotinamide all raise NAD+ — but at very different prices and with different evidence profiles. A straight comparison of RCT counts, bioavailability, and cost-per-dose.

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Evidence-graded · All categories

Best Longevity Supplements in 2025, Ranked by Clinical Evidence

The longevity supplements with the strongest human clinical trial evidence — ranked by RCT count, evidence grade, and mechanism. Updated from ClinicalTrials.gov and PubMed.

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