Origin & tradition
Sanqi (三七) has been used in Yunnan medicine for over 400 years to stop bleeding, reduce swelling, and tonify the blood. A core ingredient in Yunnan Baiyao.
Eastern tradition · Tonic Herbs
Panax Notoginseng (Sanqi) 三七 · 田七
Yunnan's best-evidenced longevity herb — cardiovascular protection, anti-inflammation, and blood-flow support with 200+ registered clinical trials.
25ClinicalTrials.gov matched
41PubMed RCT records
40Meta-analysis records
2+PubMed records
Notoginsenoside R1, Ginsenoside Rg1, Rb1Key active compound
Data definition. Matched records include all indexed medical endpoints for this intervention — not only longevity. Longevity-relevant records are screened separately and cited in the evidence summary below. Counts are matched-record volumes, not de-duplicated trials and not efficacy claims.
Why longevity buyers care
Key active: Notoginsenoside R1, Ginsenoside Rg1, Rb1.
Notoginsenosides (R1, Rg1, Rb1) activate AMPK and eNOS signalling in endothelial cells, reduce platelet aggregation, and protect against ischaemia-reperfusion injury. Multiple large RCTs confirm cardiovascular and cerebrovascular endpoints.
Effect summary
Studied health outcomes
Editorial summary — This table is curated by hand from published research consensus, not automatically calculated from our trial database. Grades reflect our interpretation of the literature. Treat as a starting point, not a definitive verdict. See the Evidence panel below for the underlying trial and paper counts sourced directly from ClinicalTrials.gov and PubMed.
| Health outcome | Effect | Magnitude | Grade |
|---|---|---|---|
| Platelet aggregation / clotting time | Decreases | Moderate | B |
| Cardiovascular markers (post-MI) | Increases | Moderate | B |
| Inflammation markers | Decreases | Minor | C |
| Microcirculation | Increases | Minor | C |
Grade: A = robust RCTs · B = several RCTs / meta-analysis · C = limited or mixed RCTs · D = observational or early data
Dosage guidance
How Panax Notoginseng (Sanqi) is typically used
- Typical dose
- 1,000–3,000 mg/day standardized extract
- Form
- capsule (standardized to notoginsenosides)
- Timing
- with meals
Also known as Sanqi (三七) or Tian Qi. Traditional hemostatic use in TCM. Do not combine with anticoagulants (warfarin, aspirin) without medical supervision — notoginsenosides affect platelet aggregation.
Informational only — not a prescription or personalised medical advice. Consult a qualified clinician before starting any supplement or medication.
Evidence summary
What the research actually says
76Evidence confidence
Human RCT evidence41 randomized controlled trials · 40 meta-analyses / systematic reviews
Strong human evidence for cardiovascular, cerebrovascular, and anti-inflammatory endpoints
Notoginsenosides (R1, Rg1, Rb1) activate AMPK and eNOS signalling in endothelial cells, reduce platelet aggregation, and protect against ischaemia-reperfusion injury. Multiple large RCTs confirm cardiovascular and cerebrovascular endpoints.
25registered clinical trials reference this intervention
2selected from 2+ PubMed papers (longevity / aging angle)
Key active: Notoginsenoside R1, Ginsenoside Rg1, Rb1 — a multi-compound botanical extract, so activity is not reducible to a single molecule.
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-09-13. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
Evidence collections
Panax Notoginseng (Sanqi) appears in
Compare the evidence
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