Eastern tradition · Chinese tonic herb
A rhizomatous orchid prized in Yunnan for neuroprotection, dizziness relief, and cognitive support — gastrodin crosses the blood-brain barrier directly.
Data definition. Matched records include all indexed medical endpoints for this intervention — not only longevity. Longevity-relevant records are screened separately and cited in the evidence summary below. Counts are matched-record volumes, not de-duplicated trials and not efficacy claims.
Tianma (天麻) has been used in Chinese medicine for over 2,000 years as a wind-eliminating, liver-calming herb for headaches, dizziness, and numbness. Grown wild in Yunnan's temperate forests, it was historically so prized it was reserved for imperial households.
Key active: Gastrodin (p-hydroxybenzyl alcohol glucoside).
Gastrodin, the primary active compound, crosses the blood-brain barrier and has demonstrated neuroprotective, anti-neuroinflammatory, and neurotrophic effects in animal and cell models. Human trials show moderate evidence for migraine prevention and mild cognitive support.
Effect summary
| Health outcome | Effect | Magnitude | Grade |
|---|---|---|---|
| Migraine frequency | Decreases | Moderate | B |
| Dizziness / vertigo | Decreases | Moderate | B |
| Neuroinflammation markers | Decreases | Minor | C |
| Cognitive function | Increases | Minor | C |
| Blood pressure | Decreases | Minor | C |
Grade: A = robust RCTs · B = several RCTs / meta-analysis · C = limited or mixed RCTs · D = observational or early data
Dosage guidance
Traditional decoction uses 3–10g dried rhizome. Yunnan's Zhaotong region is regarded as producing the highest-quality Tianma. Gastrodin injections are used clinically in China for ischemic stroke and Parkinson's — oral supplement effects are more modest.
Informational only — not a prescription or personalised medical advice. Consult a qualified clinician before starting any supplement or medication.
Evidence summary
Moderate human trial data (migraine, dizziness); strong mechanistic data
Gastrodin, the primary active compound, crosses the blood-brain barrier and has demonstrated neuroprotective, anti-neuroinflammatory, and neurotrophic effects in animal and cell models. Human trials show moderate evidence for migraine prevention and mild cognitive support.
According to PubMed and ClinicalTrials.gov: trial counts from ClinicalTrials.gov, peer-reviewed literature from PubMed. Counts auto-refresh weekly; last checked 2026-09-13. They include trials across many endpoints, not only longevity.
Informational only — not medical advice, a treatment claim, or a substitute for a qualified clinician. Evidence strength varies; we show mixed and null results on purpose.
Evidence collections
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